There is a virus going around that affects, for some reason, only Skype on infected machines. The message appears like this:
hey is this your skype profile pic? http:// sendspace [dot] com/pro/dl/8a963g?image=[your username here].
I reported it to the site and got confirmation of its deletion from the site and from another one of my friends, but that doesn't mean it won't be posted again.
If you get this message in your Skype, do NOT download the file that is on the page. I already have 2 friends that were infected. Don't let yourselves be another victim