3D Printed Ovaries are next!
9 years ago
General
New 3D Printed Ovaries Allow Infertile Mice to Give Birth
Because I’m trying to mix my porn with hard, high-concept sci-fi, I’ve been paying keen attention to science news - as each thing I postulated happening in the Lapdragonverse is invented, I get a little thrill of excitement.
Today in my newsfeed, I discovered this little gem.
So far we have penises (tested in rabbits), testicles (developed for the US army), and now ovaries. Progress continues on exowomb technologies, though no recent headlines spring to mind. Human embryos have been engineered with CRISPR, but not brought to term. Dogs, however, have, and that experiment appears to be successful. (Thanks to Chinese flakiness on IP law and bioethics, they’ve pushed their experiments forward quickly and are doing quite well. Ironically, a British bioethics board recently came to the same conclusions the Chinese did - just slower.)
Because I’m trying to mix my porn with hard, high-concept sci-fi, I’ve been paying keen attention to science news - as each thing I postulated happening in the Lapdragonverse is invented, I get a little thrill of excitement.
Today in my newsfeed, I discovered this little gem.
So far we have penises (tested in rabbits), testicles (developed for the US army), and now ovaries. Progress continues on exowomb technologies, though no recent headlines spring to mind. Human embryos have been engineered with CRISPR, but not brought to term. Dogs, however, have, and that experiment appears to be successful. (Thanks to Chinese flakiness on IP law and bioethics, they’ve pushed their experiments forward quickly and are doing quite well. Ironically, a British bioethics board recently came to the same conclusions the Chinese did - just slower.)
FA+

...Very interesting play. I think I'll have to keep that in mind.
3d printing, boring. Dissociated cells being embedded, boring. Vasculogenesis, super boring. They're nowhere near the first to show that, I don't see why they're so excited. Secreted factors from implanted cells? Been done in iPS-derived pancreas cells like 10 years ago.
My research is boring too, but at least there's a tiny bit of scientific novelty. x.-.x
And I've heard of that special kind of science hell, and how it's eaten the careers of promising young scientists who ran out of funding while trying to graduate because their peer review committee wanted like ten more years and ten times more money in new tests, completely changing the scope and goal of the experiment in the process.
As for whether it's boring or not, consider that DARPA wants a crash program to do the same thing for dudes within ten years. Doing more or less the same thing for females with a much smaller project is a triumph of getting shit done ahead of schedule and under budget.
Then again, speaking on broader terms, lack of real scientific novelty aside, this sort of research really isn't done enough. Peer reviewed literature tends to suppress things that aren't scientifically novel unless you go into engineering journals, and that doesn't really sit well with biology-trained people. So you wind up with a gap between ready-to-apply scientific knowledge, and having a reasonably validated application that is strong enough to be startup-company material. Big pharma addresses this a little bit - they tend to have some basic research groups (mechanistic) in addition to large chemical screens for initial discovery, and of course they've got the interest to push discoveries that seem promising down the pipeline into clinical trials. But if your ready-to-apply scientific knowledge isn't just a pharmacological agent, say it's a biomedical device? Awkward gap to fill, as I perceive it.
*Above statements are qualified with the limitation I'm still a grad student that doesn't know anything, and I can be wrong in both spirit and substance of any and all of the above opinions and pseudofacts.
I think the solution is to start treating biology as an engineering discipline, and creating journals to suit it.
And medical devices? There's a reason that groups like Limbitless are springing up to fill underserved markets. And there are clearly underserved markets, so...