As an omeprazole user I will warn, it loses effect over time, making you gradually take 2x to 3x more, per prescription. Also, it interferes with vitamin B and D absorption, so at high doses especially, you can develop vitamin deficiencies that can lead to... bad. Lastly, it takes a day or two before it even begins to kick in. Which also means if you have an acute acid attack/reflux, it won't do shit about fuck until tomorrow.
It also means missing a dose will be a day of hell.
Lastly, the body becomes dependant, and will actually produce even MORE acid over time, especially when the omeprazole is no longer present. This makes you chemically dependant on it even if you have the underlying problem (such as an ulcer or esophageol sphincter repair, peristaltic bypass, etc.), and can gradually cause building chemical damage to the stomach, esophagus, and common bile duct.
It also greatly increases your risk of gall stones, and can inhibit liver enzyme function worsening conditions such as chronic or acute liver damage or gilbert's syndrome.

Source: Personal life experience/use, and Gastroentertologist Ali Tauseef, who wrote 'Chron's and Colitis for Dummies'.

Thank you for sharing your experience with me. So much about this drug that I have to watch out for. 😖 I will raise these issues up with my doctor.