Amaterasu from Okami. Sorry about the weird pose. She was originally going to have her paws hovering over a shield weapon she has in the game, but I lack the ability to freehand circles with my mouse ):

I'm usually not a big digital art fan, but I really wanted to do this one and it took me a very, very long time. Just to clarify, Amaterasu was supposed to be portrayed as genderless, hence why she has male parts in the game(when you see her pee at least >.>) and is referred to as "mother of us all" by all the other gods. That alone makes it too confusing to pick a gender for her.

But I did because I'm cool. And women are cooler XD