"Your scared of Mice and Spiders, but oh so stranger is your fear, is that one day they will cross breed, to form an all powerful race of Mice-Spiders, who will immobilise human beings in giant webs, in order to steal cheese."
"I didn't say that?"
"Yea, but it'd be good wouldn't it!"

Mouse Spider Crossbreed. Evil lil blighters! Done with water colours.
Bonus points to those who know what show this was from!