Canine Cola was bottled by Lupine Liquids in Maine, a company better known for their line of pep drinks for dogs and rehydration products for "natural hunters" (an early euphanism for lycanthropes). They produced the drink under license from GeneCo--then known as Selectable Traits Inc.--with an eye toward catering to the underserved and marginalized werewolf population of the Northeast. GeneCo was confident that canidin, one of its extracts, would give the drink a delectable taste that only werewolves could experience.

Instead, it had the effect of randomly switching imbibers' forms, activating latent metamorphy genes (usually temporarily), and even temporarily manifesting lycanthropy in otherwise unaffected individuals. The effect was especially pronounced in young women, as the baby-blue coloration of the beverage turned away many other potential customers. Lupine Liquids attempted to capitalize on this by advertising Canine Cola as a thrill drink for someone who wanted a "safe" and "temporary" experience as a "natural hunter."

This led to a moral panic, one exacerbated by a notorious incident in which a Oceanside State University coed turned into a werewolf in the middle of a lecture on Pliny. Lupine Liquids was accused of having a pro-werewolf agenda, of "converting" innocents to lives of depraved lycanthropy, and of being in the employ of the Soviets (because, hey, when you're making accusations, why not?). Canine Cola was pulled from the market and Lupine Liquids shut down permanently. This led to a number of statutes banning "shape of form altering drinks" until these rules were struck down in Gnasher vs. Oceanside City. Canine Cola is a collector's item today, highly prized, though drinkers confirm that it kind of tastes like wet dog.

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