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One of the scholars at Byrgenwerth. The discovery of the old blood inspired Laurence, who believed the healing properties of the old blood were of divine nature, and was the ideal medium to transcend humanity through transfusing it into human bodies. Despite this, Provost Willem held distrust towards the substance, believing the material to be far too dangerous. Given that the Beast rune of Caryll is transcribed by him personally from the sound of a labyrinth beast, it could be that the nature of beasts was already known to Willem, and that he found the risk too high.

The two had a falling out, and unable to convince his master otherwise, Laurence took his leave, but promised to remember Willem's warnings on the danger of blood, and fear it. Even though he felt betrayed, Willem prayed that his student kept that promise. Laurence travelled to Yharnam, showing the healing properties of the ministration of old blood and eventually forming the Healing Church, becoming its first Vicar while distributing the healing blood throughout the entire city of Yharnam. But when infected blood began circulating, Laurence was among those who fell victim to the plague and transformed into the first Cleric Beast in history, and put to death.

He was revealed in the DLC to have some part in the slaughter of the Fishing Hamlet, and due to the curse laid on the hunters by Kos, Laurence was imprisoned in the Hunter's Nightmare. Left with the pain of fire and without memory, he is destined to seek the representation of his former life and mission in vain, as punishment for his misdeeds.