Here is the drawing of Nikki Wong and Caitlin Cooke from 6teen are parodying scene "Think, Mark!" Meme from Invincible Series.

Nikki: (furiously and insanity) WHY DID YOU MAKE ME INSANE!? YOU'RE SAYING ABOUT YOU'RE GIRLFRIEND WADE! THINK, CAITLIN! You'll outlast every fragile, insignificant being on this mall! You'll really stop saying about Wade!! EVERYONE AND EVERYTHING YOU KNOW WILL BE INSANE! WHAT WILL YOU HAVE AFTER BREAK UP!?

Nikki Wong and Caitlin Cooke belongs to Fresh TV
Invincible belongs to Skybound and Amazon Video