This is a rough approximation of the region's demography. I was attempting to work on a lexicon and determine place names from there. In the course of that work, I very quickly changed tack when I asked the question of who lives where. It stuck out to me that place names would largely be decided by the regional inhabitants, though not exclusively so. As I worked on the map, several characteristics that will affect the setting took shape. They are as follows:

1. Human Gradiation
Though not the majority, human are the largest of the demographic subsets when one reaches the coastal and southern regions of the Great River. This slowly fades as one goes further north, and in the farthest reaches, no known populations of humans are settled there, only wolves and ursine tribes.

2. Diversity of the Packs
There are two major lines of distinction that add variety to the family of cultures among the wolf packs. First, we have the Forest vs River Wolves. The former has historically been isolationist and extremely territorial, even rebuffing diplomatic overtures from neighboring human cultures and kingdoms. The latter entered a loose political union with the Old Kingdom of Chresten. The reigning monarch, king or queen, would have a magical ability to understand all languages. This enabled he or she to speak fluently with the different humanoid beast-folk, and facing mutual threats, a political union based mainly on economic ties and mutual defense developed. Even in the modern geopolitical arrangement, the Northern Wolves are a tenuous vassal of the bellicose Redwyrm Dominion. Their fealty is more a non-aggression pact rather than true subservience. Furthermore, they still support what is left of Chresten now colloquially called the Sacred Realm.

The second line of distinction occurs between the Western and Eastern Forest Wolves. The Eastern eventually joined their riverside kin due to a much more belligerent human culture called the Kuanan Clans. When the Dragon King's reign overturned the centuries old geopolitical framework, the Eastern Forest Wolves swore true fealty to him and his son due to their perennial competition with the Kuana.

3. Chresten and Swordedge
In the modern era, both of the kingdoms named above were conjoined forcibly into the Redwyrm Dominion by the Dragon King who was heir to Chresten by right of blood. However, the long time rivalry and cultural competition between these two disparate kingdoms continues to show up, forming an internal tension within the Redwyrm Dominion.