Team Rocket, (or whoever the fuck it is these days,) usually just tries to steal Pokemon and...I guess sell them on the black market or some shit? (Did they ever make that clear?) Me, I'm putting chemicals in the water to make the Toxicroak and Politoeds gay. Also genetically modifying the trees to produce fruit with growth hormones that make nidoqueen/kangaskhan tits bigger. Probably makes some other things bigger, but caring about these things is very un-super-villain-like.

Or maybe I need to establish a secret breeding facilities to do these sort of things. Though to be fair, the Pokemon world is dumb as fuck and I think I could do this in public, no problem. Become the Umbrella of the Pokemon universe. And then sell the milk from our nidoqueen's titties, which ALSO contains growth hormones. Now that's some super villain shit, unless you specifically only sell it to farms FOR the purpose of giving pokemon bigger tits to milk.