So many people are already hyped up over this, but they haven't even thought about so much new stuff will be in this game and changed!

-A Possibly updated Pokedex? Froslass, Regigigas, etc.
-Mightyena, Crawdaunt, and Sharpedo are now useful thanks to the special/physical split
-Marill, Gardevoir, and Mawile are now fairy-types
-The Red and Blue Orbs are now mega-stones (Probably for Minun and Plusle)
-Possibly a new girl player to continue the trend of making new girls for the remakes?