I will not complain about the trope that if you take some potion or miracle pills, essentially "bodybuilder in a bottle", that the user will instantly grow incredibly huge, muscular and strong and that is somehow stupid. But in my overly analytical mind, it does not ring right.

Because of the Laws of Thermodynamics, particularly the conservation of mass, which says, in effect, energy cannot be created or destroyed (Even though the expansion of the universe challenges this massively), simply chugging a lot of "muscle pills" will not get you the massive gains on their own, that is depicted in some works.

But what such Muscle pills, Boob pills, Dick pills, and so on will do is reduce or at least temporarily eliminate the biological limiting factors to such growth. So if one were to take their muscle pills, as directed (as more than that may cause bigger problems than needing bigger clothes), more needs to be done to get that growth.

This line of thought caused me to think about how I had worked around it this limitations. We can assume that some methods of physical training and/or medical intervention, muscle pills, are being used. Simple weight lifting and/or popping pills will not be enough but are needed. Exercise to stimulate growth is one of the major keys as you do not need to pop pills to get bigger. But you do need to EAT MORE. Excessive eating without consideration of content and without exercise, will only result in getting fat. Former Professional athletes who still eat like they are still playing get FAT, as an example.

As it is said, "You have to feed the muscles". Eating the right things and in copious amounts, inline with the training or exercise regiment, is absolutely important to getting bigger. While done for comedy, Goku in the Dragonball franchise eating several times his body weight in a single sitting is simply an exaggeration of a fact that if you train hard you need to eat lots to retain the energy to keep training and material to grow and repair the body between sessions. This is why bodybuilding is a shockingly EXPENSIVE hobby or occupation. Food, GOOD FOOD, is rarely cheap. Also the sheer amount of food needed to grow to the sizes often depicted by various artists is expensive, gluttonous, and frankly disgusting. So how do you get around this part convincingly if not realistically?

Protein drinks are the first thing I can think of. the best Protein drinks basically pack as much protein in a single 20oz serving as a 5lb beef steak. Such drinks, these are like the best of the best, are far from cheap but far less expensive that eating that much steak, less gluttonous, and certainly less disgusting, especially on the back end/waste removal. Bowel movements approach EPIC.

I have characters who eat massive amounts because they train so much and so hard, they literally hog the entire buffet table. and tell everyone else to just come back tomorrow. That was my "[Goku] eats like a monster" gag. I changed this as super nutrition bars were created. Packing upwards of 10,000 or more calories with limited self-replicating molecules, these bars are used by extremely strong and muscular members of the Power'd League and Mystic University. This is done to "feed the muscles", but also to reduce food costs, and the physical amount that needs to be eaten, saving time from having to eat so much so frequently, and reduce gluttony and disgust from eat excessively. These super nutrition bars are not cheap but far less expensive than eating that much food.

So we have, Exercise, Medicine, and Nutrition. You need all three to get huge. I did not dwell much on money, as exercise equipment will be expensive, especially the bigger, heavier, more advanced you go. Next Medicine, the muscle pills and other growth pills and potions, are not going to be cheap if you want them to be safe and effective. Finally Nutrition, because you need to take in food to fuel you training, build your body, and repair any damages incurred during or as a necessary result of training and growth. The "burn" you feel is your muscles ripping and tearing microscopically which will allow your muscles to grow larger longer and stronger.

All this said, it is NOT meant to dis or hate on art and characters (more than few I like) that depict wild growth just from taking some pills of a drinking a potion. It just got me thinking about some of much own works over time. Maybe you thought of some stuff, read or heard of some stuff along these lines.

I have not covered the effects of rapid monster growth, but if "Ultimate HULK" explained anything we should be aware of, IT HURTS...a lot.

Anyway Enjoy. Be safe in this Pandemic and this winter weather siege. Hopefully I will have power tomorrow.