Dingodile and Dr. Cortex are from Activision's Crash Bandicoot and this screenshot's taken from Valve's Garry's Mod. It is a gift for LouisFatGator.

Dingodile was enjoying his meal around some city on his day off working as the host of his cafeteria as well as a firefighter. He accidentally fell on his giant belly and somehow flattened Dr. Cortex, who is trying to find something for his evil and latest plan. He's confused about how he's got here now.