Diego has two phases when he uses the venom, though none are stable and he must be careful of using it before it goes haywire.

His first phase is what he dubs the "Full of It" phase, where he becomes more bulkier, at the cost of his skin becoming a little pale, his eye color changing, his clothes ripped, veins being visible, and a bit of loss of control. Diego is usually in this phase during action, either in a fight or punishing a worker of his that attempted to snitch on him.