I don't see why not. Sounds like a good idea.
Maybe, have all your OC's in a single folder, rather than a folder per character?

Maybe, you can also do Folders for other characters, too?
Like a Folder for "Lion King" Characters, or a Folder for "Salem"?

That a possible idea, too?

I think you should have different folders for each of your OCs so it is easier to find.

In general I think organisation is better. Also sometimes I'll see an artist with an OC I like and it can be a bit tedious working through all their works trying to find more of that OC that I like. So having a folder for each character is great.

Folders always help.

Folders makes things easier for visitors, which is always good in my opinion.